张红霞，女，1996年生，博士。2025年毕业于天津医科大学药学院，获得医学博士学位。2025年9月进入河北大学药学院工作。主要从事多肽药物的开发与利用，迄今为止，以第一作者共发表SCI论文6篇。

联系方式:E-mail: zhx9605@hbu.edu.cn

研究方向：

1.自组装多肽在抗肿瘤方向的研究

2.新型多肽药物的开发与利用

科研项目：

河北省自然科学基金青年科学基金项目，2026.01-2028.12，5万，主持

代表性论著：

1.Hongxia Zhang, Ming Ji, Yamei Wang, Mengmeng Jiang, Zongyu Lv, Gongyu Li*, Lulu Wang*, Zhen Zheng*. Intrinsic PD-L1 Degradation Induced by a Novel Self-Assembling Hexapeptide for Enhanced Cancer Immunotherapy. Advanced Science. 2025, 12, 2410145. (Q1, IF: 14.3).

2.Hongxia Zhang, Liyuan Peng, Weida Qin, Deying Jia, Rui Zhao, Mengmeng Jiang, Ming Ji, Lulu Wang, Gongyu Li*, Zhen Zheng*. Enhanced chemotherapy and anti-metastasis with in situ nanosphere-to-nanofiber transition. Nano Today. 2024, 54, 102122. (Q1, IF: 13.2).

3.Hongxia Zhang, Yamei Wang, Mengmeng Jiang, Kunyu Wang, Jingru Yan, Gongyu Li, Zhen Zheng*. Inherently Anti-Metastatic Peptide Hydrogels for Sonodynamic-Amplified Ferroptosis in Cancer Therapy. Materials Today Bio. 2025, 32, 101688. (Q1, IF: 11.0).

4.Hongxia Zhang, Weiyu Xing, Yang Zhang, Jiaxin Zhou, Yulu Wang, Gongyu Li, Zhen Zheng*. Self-assembling peptide alters cell death pathway for pyroptosis-enhanced immune activation. Journal of Medicinal Chemistry. 2025, 68, 16188-16196. (Q1, IF: 6.9).

5.Hongxia Zhang, Mengmeng Jiang, Weiyu Xing, Rui Zhao, Gongyu Li, Zhen Zheng*. Peptide-IR820 Conjugate: A Promising Strategy for Efficient Vascular Disruption and Hypoxia Induction in Melanoma. ACS Applied Materials & Interfaces. 2024, 16, 40641-40652. (Q1, IF:8.5).

6.Hongxia Zhang, Haohua Lin, Dan Su, Dechao Yang, and Jianyong Liu*. Enzyme-Activated Multifunctional Prodrug Combining SiteSpecific Chemotherapy with Light-Triggered Photodynamic Therapy. Molecular Pharmaceutics. 2022, 19, 630-641. (Q1, IF: 4.5).