
刘凤洁,博士,博士后,助理研究员。2014年本科毕业于河北医科大学,获药学学士学位,2020年硕博连读毕业于中国药科大学,获生药学博士学位,2023年于中国药科大学中药学博士后流动站出站,同年入职河北大学药学院。近年来,主持国家自然科学基金青年项目1项,河北省高等学校科学技术研究项目1项,以第一作者或通讯作者身份发表SCI论文7篇。
联系方式:liufj_cpu@126.com
主讲课程及研究方向
1.主讲课程:生药学、药用植物学、生药学实验
2.研究方向:中药药效物质与作用机制研究
科研项目
1.成分谱-靶点谱-互作网络探究蒲公英治疗三阴乳腺癌的药效物质与作用机制,国家自然科学基金青年科学基金,82104363,2022/1~2024/12,30万,结题,主持。
2.蒲公英效应物质及其协同抗肿瘤作用机制研究,河北省高等学校科学技术研究青年拔尖人才项目,BJK2024153,2024/01 ~2026/12,10万,在研,主持。
代表性论文
1. Yu T, Chen JM, Liu W, Zhao JQ, Li P,Liu FJ*, Jiang,Y* Li HJ*, In-depth characterization of cycloartane triterpenoids and discovery of species-specific markers from three Cimicifuga species guided by a strategy that integrates in-source fragment elimination, diagnostic ion recognition, and feature-based molecular networking, Journal of Chromatography A, 2024, 1728: 465015.
2.Liu FJ1, Chen XY1, Yang J, Zhao Z, Wang QL, Li P, Jiang Y*, Li HJ*. Revealing active components and action mechanism of Fritillariae Bulbus against non-small cell lung cancer through spectrum-effect relationship and proteomics. Phytomedicine, 2023, 110: 154635.
3.Liu FJ1*, Yang J1, Chen XY, Yu T, Ni H, Feng L, Li P, Li HJ*. Chemometrics integrated with in silico pharmacology to reveal antioxidative and anti-inflammatory markers of dandelion for its quality control. Chinese Medicine, 2022, 17: 125.
4.Liu FJ, Jiang Y, Li P, Liu YD, Yao ZP*, Xin GZ*, Li HJ*. Untargeted metabolomics coupled with chemometric analysis reveals species-specific steroidal alkaloids for the authentication of medicinal Fritillariae Bulbus and relevant products, Journal of Chromatography A, 2020, 1612: 460630.
5.Liu FJ, Jiang Y, Li P*, Liu YD, Xin GZ, Yao ZP*, Li HJ*. Diagnostic fragmentation-assisted mass spectral networking coupled with in silico dereplication for deep annotation of steroidal alkaloids in medicinal Fritillariae Bulbus, Journal of Mass Spectrometry, 2020, 55: e4528.
6.Liu FJ, Liang D, Miao LY, Li P, Li HJ*. Liver-specific metabolomics characterizes the hepatoprotective effect of saponin-enriched Celosiae Semen extract on mice with nonalcoholic fatty liver disease, Journal of Functional Foods, 2018, 42: 185-194.
7.Liu FJ, Zhu ZH, Jiang Y*, Li HJ*. A pair of cyclopeptide epimers from the seeds of Celosia argentea. Chinese Journal of Natural Medicine, 2018, 16: 63-69
发明专利
1.刘凤洁,李会军,杨娇,菊苣酸在制备三阴乳腺癌治疗药物中的应用, 2022-07-28,中国, CN202210897177.0
2.李会军,刘凤洁,杨娇,木犀草素和菊苣酸联合在制备乳腺癌治疗药物中的应用, 2023-9-8,中国, CN202210896723.9