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宋雪晴

更新时间:2022-08-17 14:57:28点击次数:

      宋雪晴,女,博士,硕士生导师。2020年于天津医科大学药学院获药理学专业博士学位。主要从事抗肿瘤药物的设计合成和体内外活性机制研究工作,主持河北大学高层次人才科研启动项目1项,河北省自然科学基金青年项目1项;参与国家级、省级科研项目6项。在相关领域国际学术期刊发表SCI论文16篇。E-mail: sxqing@hbu.edu.cn

代表性论文

[1] Zhong-Ying Ma1,Xue-Qing Song1, Juan-Juan Hu1, Dong-Bo Wang, Xiao-Jing Ding, Rui-Ping Liu, Miao-Liang Dai, Fan-Yin Meng, Jing-Yuan Xu*. Ketoplatin in triple-negative breast cancer cells MDA-MB-231: High efficacy and low toxicity, and positive impact on inflammatory microenvironment. Biochemical Pharmacology, 2021, 188, 114523.

[2]Xue-Qing Song1, Rui-Ping Liu1, Shu-Qing Wang1, Zhe Li, Zhong-Ying Ma, Ran Zhang, Cheng-Zhi Xie, Xin Qiao, and Jing-Yuan Xu*. Anticancer Melatplatin prodrugs: high effect and low toxicity, MT1-ER-target and immune response in vivo.Journal of Medicinal Chemistry, 2020, 63, 6096−6106.

[3] Ming Liu1,Xue-Qing Song1, Yuan-Di Wu, Jing Qian*, and Jing-Yuan Xu*. Cu(II)-TACN complexes selectively induced antitumor activities in HepG-2 cells by DNA damage and mitochondrial-ROS-mediated apoptosis.Dalton Transactions, 2020, 49, 114–123.

[4]Xue-Qing Song1, Zhong-Ying Ma1, Yi-Gang Wu1, Miao-Liang Dai, Dong-Bo Wang, Jing-Yuan Xu* and Yangzhong Liu*. New NSAID-Pt(IV) prodrugs to suppress metastasis and invasion of tumor cells and enhance anti-tumor effectin vitro andin vivo[J].European Journal of Medicinal Chemistry, 2019, 167, 377−387.

[5]Xue-Qing Song1, Ya-Hong Liu1, Jia Shao1, Zhen-Lei Zhang, Cheng-Zhi Xie, Xin Qiao, Wei-Guo Bao*, and Jing-Yuan Xu*. Rapid induction of apoptosis in tumor cells treated with a new platinum(II) complex based on amino-thiazolidinone[J].European Journal of Medicinal Chemistry, 2018, 157, 188−197.