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宋雪晴

更新时间:2020-09-10 16:56:49点击次数:640次

宋雪晴,女,博士。本科就读于河北师范大学化学与材料科学学院药学专业,获理学学士学位。2015年考入天津医科大学药学院,通过硕博连读获得药理学专业医学博士学位。主要从事新型铂类抗肿瘤药物的设计和体内外抗癌活性机制的研究。在Journal of Medicinal Chemistry, European Journal of Medicinal Chemistry等国际学术期刊发表SCI论文多篇。邮箱:sxqing1992@163.com

代表性论文

[1] Xue-Qing Song1, Rui-Ping Liu1, Shu-Qing Wang1, Zhe Li, Zhong-Ying Ma, Ran Zhang, Cheng-Zhi Xie, Xin Qiao, and Jing-Yuan Xu*. Anticancer Melatplatin prodrugs: high effect and low toxicity, MT1-ER-target and immune response in vivo. Journal of Medicinal Chemistry, 2020, 63, 6096−6106.

[2] Ming Liu1, Xue-Qing Song1, Yuan-Di Wu, Jing Qian*, and Jing-Yuan Xu*. Cu(II)-TACN complexes selectively induced antitumor activities in HepG-2 cells by DNA damage and mitochondrial-ROS-mediated apoptosis. Dalton Transactions, 2020, 49, 114–123.

[3] Xue-Qing Song1, Zhong-Ying Ma1, Yi-Gang Wu1, Miao-Liang Dai, Dong-Bo Wang, Jing-Yuan Xu* and Yangzhong Liu*. New NSAID-Pt(IV) prodrugs to suppress metastasis and invasion of tumor cells and enhance anti-tumor effect in vitro and in vivo[J]. European Journal of Medicinal Chemistry, 2019, 167, 377−387.

[4] Xue-Qing Song1, Ya-Hong Liu1, Jia Shao1, Zhen-Lei Zhang, Cheng-Zhi Xie, Xin Qiao, Wei-Guo Bao*, and Jing-Yuan Xu*. Rapid induction of apoptosis in tumor cells treated with a new platinum(II) complex based on amino-thiazolidinone[J]. European Journal of Medicinal Chemistry, 2018, 157, 188−197.

[5] Zhong-Ying Ma1, Dong-Bo Wang1, Xue-Qing Song1, Qian Chen, Yi-Gang Wu, Jing-Yi Li, Shi-Hao Cheng, and Jing-Yuan Xu*. Chlorambucil-conjugated platinum(IV) prodrugs to treat triple-negative breast cancer in vitro and in vivo[J]. European Journal of Medicinal Chemistry, 2018, 157, 1292−1299.

[6] Ran Zhang, Xue-Qing Song, Rui-Ping Liu, Zhong-Ying Ma, Jing-Yuan Xu*. Fuplatin: an Efficient and Low-toxic Dual-prodrug[J]. Journal of Medicinal Chemistry, 2019, 62, 4543−4554.

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